Focused on young 20somethings Blue Reynolds (an aspiring music mogul), Tommy James (an aspiring artist), Mamie Lopez (an underground DJ), Jade Taylor (Mamie's best friend and aspiring doctor), Jayson Martin (a gifted but unknown rapper), and Zoe Daniels (an aspiring fashion designer), 8 Days a Week follows the group of friends on through their breakthroughs, and struggles, on their journeys toward success and fame.