The action takes place in Ephesus in ancient Asia Minor, and the story concerns the efforts of two boys from Syracuse, Anthipholus and his servant Dromio, to find their long-lost twins who, for reason of plot confusion, are also named Anthipholus and Dromio. Complications arise when the wife of the Ephesians, Adriana and her servant Luce, mistake the two strangers for their husband, though the couples eventually get sorted out after Adriana's sister Luciana and the Syracuse Antipholus admit their love.