Zoe, Duncan, Jack & Jane is a series that saw two lives. First: The first series follows four students (see title of show) at a private high school, Fielding Mellish Prep, in Manhattan. Even in the first series, the show focus was on Zoe (the other kids in the title are friends of Zoe's (Selma Blair), the twins Jack (a pre-Lex Luthor Michael Rosenbaum) and Jane (Azura Skye), and the loser Duncan (David Moscow)). The first series lasted 13 episodes before being halted for a remix. Second: The second series was just called "Zoe" and follows Zoe a few years later as a college student studying psychology. Most of the characters from the first 13 episodes, turn up in the second "Zoe" 13 episodes.