"Detective McLean" revolves around Allison McLean (Kelli Williams), a tough and experienced police detective, mother and wife in suburban Seattle. When she and her police partner (Dion Johnstone) must arrest her brother (Luke Perry) for aggravated assault, her world drastically changes as he's convicted and sent to prison, leaving his two teenagers teetering on the brink of foster care. Ultimately, she takes them into her home, ending up with four teenagers to raise as well as her demanding job solving local crimes.