Annihilate is a coming of age story about a young man named Justin who accepts a job as a house sitter for a few months. He is trying to overcome his depression and is taking antidepressants, unaware of the side effects it has. He forms relationships with a young boy named Bart and the gorgeous, free spirited, vegan, animal lover, ruthless Abigail who help Justin overcome his depression. A story that focuses on the little details that makes humans, human and the little things worth living for.