Doomed tells the story of Leandro (Cauã Reymond, from Brazil Avenue), a sophisticated sommelier and a real Don Juan. After returning to his native city, he has a romance with Celeste (Dira Paes), who is married to a powerful businessman. Due to his insatiable appetite for women, he also becomes involved with Isabel (Patrícia Pillar), the wife of his boss, Jaime (Murilo Benício). For Leandro, seducing women is just a game until he is taken by surprise upon falling in love with Antônia (Isis Valverde), the couple's daughter. This young girl makes him question his convictions and together, they are thrown into a thrilling story of desire, jealousy and revenge. Antônia's mother is discreet and totally devoted to her family. Torn between her daughter's and her husband's desires, she tries, unsuccessfully, to ease the bitter feelings between the two. Celeste, on the other hand, is a passionate and seductive woman who hides her affair with the sommelier from everyone.