Young, nerdy First Nations science genius/social misfit Fred, with his female science buddy, Donna, get a hold of a scientifically formulated, herb-based and largely untested love potion. The source of the magic elixir is Fred's long lost, ex-scientist-now- Traditional-healer, Uncle John. His 'love potion' seems to work, as Fred finds himself 'loved' by his dream babe Caroline and seems to be accepted by the 'cool-to-be-cruel' crowd. However, soon enough the experiment backfires and Fred collapses. To save him, Donna has to extend herself in ways she was afraid to ever since she first met Fred. The situation also requires Dr. John to face his own dilemmas about love and relationships. Dr. John tells the story in a flashback, several months after Fred's experience with his 'love potion'. Dr. John is now living alone, away from everything and everybody. His solitude is disturbed by a request to help an old, depressed horse and a down-on-herself teenage girl.