克里斯·洛克
Chris Rock
饰：奥兹 Osmosis Jones
劳伦斯·菲什伯恩
Laurence Fishburne
饰：瑞克斯 Thrax
大卫·海德·皮尔斯
David Hyde Pierce
饰：德雷克斯 Drix
布兰蒂·诺维德
Brandy Norwood
饰：Leah
威廉·夏特纳
William Shatner
饰：Mayor Phlegmming
朗·霍华德
Ron Howard
饰：Tom Colonic
卡洛斯·阿拉斯拉奇
Carlos Alazraqui
饰：Additional Character Voice
Keith Anthony
饰：Additional Character Voice
埃迪·巴特
Eddie Barth
饰：Additional Character Voice
保罗·克里斯汀
Paul Christie
饰：Additional Character Voice
Janis Dardaris
Janis Dardaris
饰：Additional Character Voice
安东尼奥·法加斯
Antonio Fargas
饰：Additional Character Voice
埃迪·弗里森
Eddie Frierson
饰：Additional Character Voice
唐纳德·富利洛夫
Donald Fullilove
饰：Additional Character Voice (as Don Fullilove)
杰姬·戈诺
Jackie Gonneau
饰：Additional Character Voice
Shannon Gregory
饰：Additional Character Voice
利弗·赫顿
Rif Hutton
饰：Additional Character Voice
理查德·史蒂文·霍维茨
Richard Steven Horvitz
饰：Additional Character Voice (as Richard Horvitz)
Joyce Kurtz
饰：Additional Character Voice
安妮·洛克哈特
Anne Lockhart
饰：Additional Character Voice
雪莉·琳
Sherry Lynn
饰：Additional Character Voice
丹尼·曼
Danny Mann
饰：Additional Character Voice
米凯·麦高万
Mickie McGowan
饰：Additional Character Voice
'Stuttering' John Melendez
'Stuttering' John Melendez
饰：Additional Character Voice
Héctor Mercado
Héctor Mercado
饰：Additional Character Voice
保罗·佩普
Paul Pape
饰：Additional Character Voice
Chris Phillips
饰：Additional Character Voice
Lynne Redding
饰：Additional Character Voice
Al Rodrigo
Al Rodrigo
饰：Additional Character Voice
Herschel Sparber
Herschel Sparber
饰：Additional Character Voice
道格·斯通
Doug Stone
饰：Additional Character Voice
史蒂夫·萨斯坎德
Steve Susskind
饰：Additional Character Voice
Paul Tuerpe
Paul Tuerpe
饰：Additional Character Voice
罗伯特·维斯多姆
Robert Wisdom
饰：Additional Character Voice
比尔·默瑞
Bill Murray
饰：弗兰克 Frank Detomello
莫莉·香侬
Molly Shannon
饰：Mrs. Boyd
克里斯·艾略特
Chris Elliott
饰：Bob
丹尼·墨菲
Danny Murphy
饰：Zookeeper Superintendent
Will Dunn
饰：Oyster Boy
Jackie Flynn
饰：School Janitor
Kelsey Jordan
饰：Bus Girl #1
Anna Byers
Anna Byers
饰：Bus Girl #2
Jesse Peter
Jesse Peter
饰：Laughing Boy
John-Eliot Jordan
John-Eliot Jordan
饰：Pea Soup Manager (as John Jordan)
Nancy Byers
饰：Pea Soup Supervisor
Kevin J. Flynn
饰：Docky's Clamshack Waiter (as Kevin Flynn)
埃里卡·比尔曼
Erika Bierman
饰：Dreamy Photographer
Kathryn Frick
饰：Nurse #1
Nicki Tyler Flynn
Nicki Tyler Flynn
饰：Nurse #2 (as Nikki Tyler-Flynn)
Elizabeth Jordan
Elizabeth Jordan
饰：Nurse #3
泽恩·格斯纳
Zen Gesner
饰：Emergency Room Doctor #1
John Britten
饰：The Zoo Visitors & Staff
巴巴拉·奥康纳
Barbara O'Connor
饰：The Zoo Visitors & Staff
Ruth Meyer
饰：The Zoo Visitors & Staff
Bill Beauchene
饰：The Science Fair Contestants & Families
博·克利里
Bo Cleary
饰：Pea Soup Staff
Docky
Docky
饰：The Bikini Gang
Brian Mone
饰：Police Officer
Sean Fitzgerald
饰：Police Officer
Beth Jordan
饰：The Emergency Room Nurse
Kathy Farrelly
饰：Nurse (uncredited)
肖恩·福格帝
Shawn Fogarty
饰：Father at science fair (uncredited)
卡姆登·蒙森
Camden Munson
饰：(uncredited)
乔·西尔沃
Joel Silver
饰：Police Chief (uncredited)
本·斯坦
Ben Stein
饰：Doc (uncredited)
Ben Urann
饰：Student (uncredited)
Jillian Wheeler
饰：Student (uncredited)
摇滚小子
Kid Rock
饰：Kidney Rock
Kenny Olson
饰：Kidney Rock
Jason Krause
饰：Kidney Rock
Joe C.
饰：Kidney Rock
Stefanie Eulinberg
饰：Kidney Rock
Jimmie Bones
饰：Kidney Rock
Uncle Kracker
饰：Kidney Rock
乔纳森·亚当斯
Jonathan Adams
饰：Additional Character Voice
Sally Ann Brooks
Sally Ann Brooks
饰：Additional Character Voice
罗杰·布帕斯
Rodger Bumpass
饰：Additional Character Voice
Michael Carven
饰：Additional Character Voice
Wendy Dillon
饰：Additional Character Voice
Art Kimbro
饰：Additional Character Voice
Marilyn Pasekoff
饰：Additional Character Voice
凯丽·通巴齐安
Keri Tombazian
饰：Additional Character Voice
Elena Franklin
饰：Shane Detomello
Jack McCullough
Jack McCullough
饰：Zookeeper
Kathy Wege
饰：Mrs. Claris, Volcano Lady
马克·海曼
Marc Hyman
饰：Emergency Room Doctor #2
塞克·潘
Zak Penn
饰：Emergency Room Doctor #3
Bob O'Brien
饰：The Zoo Visitors & Staff
Tom Beachene
饰：The Zoo Visitors & Staff
Diane Conrad
饰：The Zoo Visitors & Staff
Judy Conrad
饰：The Zoo Visitors & Staff
Bob Fennessy
饰：The Zoo Visitors & Staff
Katie Britten
饰：The Zoo Visitors & Staff
Marlene Malone
饰：The Zoo Visitors & Staff
Grady O'Connor
饰：The Zoo Visitors & Staff
Jacqueline Wentzell
饰：The Zoo Visitors & Staff
Morgan Wentzell
饰：The Zoo Visitors & Staff
Jamie Heres
饰：The Zoo Visitors & Staff
Jimmy Heres
饰：The Zoo Visitors & Staff
Thomas Jordan
饰：The Zoo Visitors & Staff
Mandy Marsh
饰：The Zoo Visitors & Staff
Tommy Barbieri
饰：The Zoo Visitors & Staff
Allison Barbieri
饰：The Zoo Visitors & Staff
Erica Johnson
Erica Johnson
饰：The Zoo Visitors & Staff
Sydney J. Bartholomew Jr.
饰：The Zoo Visitors & Staff (as Sidney Jackson Bartholomew Jr.)
Buzz Dunn
饰：The Science Fair Contestants & Families
Laura Dunn
饰：The Science Fair Contestants & Families
Krista-Jean Forand
饰：The Science Fair Contestants & Families
Kena Flynn
饰：The Science Fair Contestants & Families
Christina Kacmar
饰：The Science Fair Contestants & Families
Diana O'Donnell
Diana O'Donnell
饰：The Science Fair Contestants & Families
Dick Silva
饰：The Science Fair Contestants & Families
Allison Kacmar
饰：The Science Fair Contestants & Families
Nicole Brathwaite
饰：The Volcano Gal
Emily O'Day
饰：The Volcano Gal
Brianna Cabral
饰：The Volcano Gal
Catherine Dunphy
饰：The Volcano Gal
Chandler Vuilleumier
饰：The Volcano Gal
Bill Wade
饰：Pea Soup Staff
Bruce McIntyre
饰：Pea Soup Staff
Colleen O'Donnell
饰：Docky's Clamshack
Maryjane Foy
饰：Docky's Clamshack
Jo Ann Nicewicz
饰：Docky's Clamshack
Jillian Nicewicz
饰：Docky's Clamshack
Heidi Hetzel
饰：The Bikini Gang
Patricia Guiggey
饰：The Bikini Gang
Rachael Kasner
饰：The Bikini Gang
George Kouri
饰：The Bikini Gang
Joe Murphy
饰：The Bikini Gang
Dick Rubin
饰：The Bikini Gang
Amy Suhay
饰：The Bikini Gang
Mattie Ostiguy
饰：The Emergency Room Nurse
Grace Costa
饰：The Emergency Room Nurse
Maura O'Brien
饰：The Emergency Room Nurse
Cortney Urichuck
饰：Student (uncredited)
Megan Urichuck
饰：Student (uncredited)
John Melendez
Nikki Tyler-Flynn
饰：Nurse #2
A.B. Farrelly
饰：Bus Girl #2,(as Anna Byers)