Julie Messinger has it made. She is a New York housewife whose husband, Richard, is an editor for a prominent photography magazine. They have a small circle of friends, including well-meaning, but inept Dr. Timothy Spector, photographer Cal Whiting and Cal's live-in girlfriend Miranda. Julie's mother spends her days getting pedicures and manicures, applying make-up and fake eye-lashes and buying expensive clothes, all the while criticizing her daughter for her looks and behavior. When Richard goes into the hospital for a minor mole-removal surgery, Julie gets more than she bargained for. Richard suffers from complications and goes into a coma, supposedly caused by a rare surgical factor, and she gathers friends and family together, culminating in a hilarious "quasi-cocktail-party" scene in the blood donation center of the hospital.