Me and Luke is a family story about a young father and his newborn son. Matt, who is nineteen, goes to the hospital to see his baby. At the hospital, he discovers, his young girlfriend has already made arrangements for a couple to the adopt their baby boy. Matt has no family and when he sees Luke for the first time, like fathers everywhere, he falls in love with him. He finally has made the connection he's longed for. With the adoption imminent and no means to stop it - Matt takes Luke out of the hospital to his grandmother's house. The three form an off-kilter family unit. But can Matt and Luke win against the odds and stay together as a family...?