Beatriz Pengson, or simply Betty is an aesthetically-challenged career-oriented girl who happens to work in a posh advertising agency known as Eco Moda Manila. In an industry where everyone thrives on beauty and perfection, her lack of good looks and outdated sense of fashion make her an instant outcast amongst her superficial colleagues. Despite her shortcomings, Betty's capabilities and innate kindheartedness have gained her a set of loyal friends. Betty's lackluster life, however, heads a turn for the better (or is it for worse?) when she meets the man of her dreams Armando, the President of Eco Moda Manila. How will Betty catch the elusive heart of someone who's way out of her league? Is it possible that a good-looking guy like Armando will eventually fall in love with a certified ugly duckling?