Mel Cobb leads a lonely existence in an apartment filled with clutter, his only contact with the outside world being as a weekend tele-marketer for a start-up newspaper which features stories on city road, bridge and tunnel construction workers in order to alleviate road rage among motorists who are stuck in traffic. One morning, Cobb listens to a radio news report indicating that left-handed people die younger than right-handers, and so makes the decision to convert to left-handedness as a means of shortening his life span. His attempt at becoming a lefty leads to an interesting turn of events which suggest that he may be at the start of a never-ending cycle.