When Sunshine Valley settlers face disaster because of a food shortage and medicine shortage, Gene Autry and Dan Coleman, father of Gene`s friend Jennifer, buy supplies in Trail`s End, but additional supplies promised by the operators of the town`s only store, Lola Riker and her partner Ross McLain are not forthcoming. With the aid of the law and his friend Smiley, Gene gets a shipment through to Sunshine Valley, battling off a hi-jacking attempt but too late to prevent a little girl, Judy, from dying because of a lack of medicine. Gene heads for a showdown battle with McLain.