At ICP Corporation, the race is on to finish and bring to market, a new technology. John Alcott is the engineer that develops it and because of his talent he is promoted to Director of Technology. But John is a nerd with no social skills and the victim of countless pranks and jokes by his jealous co-workers. They decide to pull the ultimate prank and invite John to a night of celebration at Club 2000. Unknown by John, the invitation is a set-up. His so-called friends arrange a meeting with hooker, Alicia Mantry. At the club the prank goes off as planned with some unpleasant side effects. John`s humiliation is complete and it causes him to change from a nerd to a suave and debonair gentleman. In the club`s men`s room, he meets the strange Jamaican valet, Maurice, who gives him a concoction called JuJu that promises to change his life. John undergoes a transformation. In an effort to achieve revenge on his evil perpetrators, he may also have become an evil serial killer.