Dr. Simon Locke was a handsome young physician who moved to the small town of Dixon Mills, Canada, where he set up practice with his curmudgeonly older mentor Dr. Andrew Sellers. Louise Wynn was their nurse, as they treated crime victims, abused children and a variety of diseases, some serious, others not so. In the second season, Dr. Locke left Dixon Mills, Dr. Sellers and Nurse Wynn behind for the big city, where he joined the police emergency unit and received a new boss in former Dixon Mills cop Dan Palmer. Palmer was later replaced by Lt. Gordon, as Locke investigated a number of crimes associated with the patients he was treating.