Fantastic Man is about Fredo (Vic Sotto), a naive and gawky laboratory assistant to Professor Manalo (Michael V.). Fredo is also the professor's regular guniea pig for his experiments which are often disastrous to any human being. Then one time a librarian, Helen (Ara Mina)who is frustrated super hero wanabe, tells both Fredo and Prof. Manalo about an article she read of an orb located in Intramuros that was said to give out powers to whoever posesses it. They all journeyed to Intramuros in search for the orb and found inside a dead alien's body. Because of Fredo's clumsiness, the orb got lost. But it actually went into Fredo's shirt pocket. He then absorbs all the powers when he accidentally touched the orb and he became Fantastic Man! With superpowers, transformations and quickness can Fantastic Man save his town in the hands of his arch-enemy Diabolica (Ara Mina) whose powers can absorb almost anything?