The Long-Term Side Effect is the quirky, awkward comedy re-imagined. Lei Kelly is a survivor of pancreatic cancer. She was diagnosed at age 22 and part of an experimental treatment that cured her, but left a strange side effect: Lei has completely stopped aging. Now 40 years old, Lei still appears 22, suffering from acne and often mistaken as her teenage daughter's sister. Having spent the last 18 years obsessing over her 'condition,' Lei has completely distanced herself from the world. When her husband, unable to take her detachment any longer, finally packs his bags and walks out, Lei realizes she needs to restart.