The series revolves around two 13-year-old best friends, Paige and Frankie, who write funny songs and create music videos for their online channel, titled Bizaardvark, which has 10,000 subscribers. The amateur musicians get to work from a creative studio space that they hope will take their videos to the next level. In their cool new environment, and with the help of family and friends, the girls will embark on a series of comedic adventures in their quest to become online stars.